Ciallis 20 with Tadalafil for ED Treatment

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Gui í a de Salud Masculina

  1. I. the mechanism of action
  2. II. Points for attention in use

Cialis (tadalafil) 20mg is a drug used to treat erectile dysfunction (ED) in men.

Ciallis 20 with Tadalafil for ED Treatment

I. the mechanism of action

1 、Vasodilation

Tadalafil reduces the degradation of cyclic guanosine monophosphate (cGMP) by inhibiting the activity of phosphodiesterase 5 (PDE5). CGMP is a signal molecule that plays an important role in the smooth muscle cells of corpus cavernosum. When sexual stimulation leads to the release of nitric oxide (NO), NO activates guanylate cyclase and converts guanosine triphosphate (GTP) into cGMP,cGMP, which causes smooth muscle relaxation of corpus cavernosum and blood flow into the penis. To achieve an erection.

2 、Improvement of erectile function

-under sexual stimulation, Cialis 20mg can promote penile erection, and can help patients maintain erection and improve the quality of their sex life.

II. Points for attention in use

1 、Take medicine as directed by the doctor

-the drug should be used under the guidance of a doctor, who will determine the appropriate dose and frequency according to the patient's age, health status, history of other diseases (such as cardiovascular disease, hypotension, etc.) and other drugs being taken.

2 、Medication time

-it is usually taken as needed about 30 minutes to 12 hours before sexual activity, but it should be noted that it should be taken at most once a day.

3 、Adverse reaction

Common reaction

Headache is one of the more common adverse reactions, which may be related to the vasodilation effect of drugs, facial flushing is also more common, mainly due to vasodilation leading to increased skin blood flow, indigestion is also a possible symptom, including stomach discomfort, nausea and so on.

A rare but severe reaction

-it may cause hypotension, especially when used in conjunction with certain antihypertensive drugs, and may also affect vision. Although this situation is rare, it has been reported that non-arterial anterior ischemic optic neuropathy (NAION) may occur, resulting in vision loss or loss.

4 、Interaction with other drugs

Tadalafil cannot be used in conjunction with organic nitrates (such as nitroglycerin) because the combination of the two may cause severe hypotension or even life-threatening. When used with some antihypertensive drugs, antifungal drugs (such as ketoconazole, itraconazole) and antiviral drugs (such as ritonavir), it may affect the metabolism of tadalafil and increase the concentration of the drug in the body, thereby increasing the risk of adverse reactions.

If you have erectile dysfunction-related problems, it is not recommended to purchase Cialis 20mg, you should first see a doctor to evaluate the condition and get professional treatment advice.


1 、Basic information:

-Cialis is a PDE5 inhibitor developed and produced by Eli Lilly Pharmaceuticals of the United States.

-there are two main specifications of Xiaili products listed in the Chinese market: 20mg (on demand) and 5mg (once a day).

2 、Composition and character:

-the main ingredient of this product is tadalafil, the chemical name is complex, please refer to the relevant literature.

-the 20mg film is yellow and almond shaped with the word "C 20" on one side.

3 、Indication:

-mainly used in the treatment of erectile dysfunction (ED).

4 、Usage and dosage:

-when taking it on demand, it is recommended that the initial dose is 10mg. It is not affected by eating before sex. If the effect is not significant, you can take 20mg. The maximum frequency of taking medicine is once a day.

-when taking 2.5mg once a day, it is recommended that the initial dose be taken at about the same time every day, regardless of when to have sex. According to individual efficacy and tolerance, the dose can be increased to 5mg.

5 、Adverse reaction:

Common side effects include headache, indigestion, back pain, myalgia, nasopharyngitis, nasal congestion and facial flushing.

6 、Taboo:

-patients who are taking any form of nitrate drugs are strictly prohibited from taking tadalafil tablets as they may enhance the antihypertensive effect of nitrate drugs.

-patients who are not known to be allergic to tadala should not take it.

7 、Matters needing attention:

-doctors should consider the patient's cardiovascular health, as heart risk is related to sexual behavior.

It is not recommended for specific groups of people, such as patients with recent myocardial infarction, patients with unstable angina pectoris, patients with severe heart failure, patients with uncontrolled arrhythmia or hypertension.

8 、Drug interaction:

The possibility of pharmacokinetic interaction with tadalafil tablets includes interaction with nitrate drugs, α-receptor blockers, antihypertensive drugs and so on.

9 、Medication for special population:

-pregnant and lactating women should not use tadalafil tablets.

-the safety and effectiveness of children have not yet been established.

-elderly patients do not need to adjust the dose according to age, but some older individuals should be considered to be more sensitive to drugs.

The information is for reference only and does not constitute professional medical advice. Be sure to consult your doctor or pharmacist before using any drug.

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