Sildenafil (Viagra) and Tadalafil (Cialis): PDE5 inhibitors for blood flow

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Taking tadalafil and sildenafil together is not recommended.

1. Medical reasons

-both drugs are type 5 phosphodiesterase inhibitors (PDE-5) and have the same main action mechanism, which is to increase blood flow to the penis to facilitate erection. Taking them in combination increases the risk of serious side effects.

-Common side effects of these drugs individually include headaches, dizziness, blurred vision, decreased blood pressure and, in combination, these effects can be more intense and potentially dangerous.

Sildenafil (Viagra) and Tadalafil (Cialis): PDE5 inhibitors for blood flow

-there is also a higher risk of hypotension (low blood pressure), which can cause dizziness, fainting and, in extreme cases, organ damage due to excessive decrease in systemic blood pressure.

If a patient does not respond adequately to a single drug, he or she should consult a specialist physician (for example, a urologist or a sexual health doctor) to evaluate other appropriate and safe therapeutic options, rather than self-administering the combination of these two drugs.


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